Preheat the oven to 400°F.
In a bowl, combine the ground antelope, crushed crackers, egg, garlic, ricotta cheese, basil, thyme, oregano, onion powder, and salt. Mix gently until just combined. Roll into 12 meatballs.
Place the meatballs on a baking sheet lined with foil or parchment paper and bake for 15 minutes.
While the meatballs bake, heat an oven-proof skillet over medium-low heat. Add the butter and orzo pasta, then stir in the marinara sauce and cottage cheese. Cook for 12–14 minutes, stirring occasionally, until the orzo is tender.
Remove the meatballs from the oven and nestle them into the skillet. Top with sliced mozzarella and grated Parmesan cheese.
Transfer the skillet to the oven and bake until the cheese is melted and bubbling, about 10 minutes. For a golden, slightly crisp top, broil for 1–2 minutes at the end.
Serve the antelope meatballs with a crisp green salad and slices of sourdough bread.